Nueva Palmira is a port city located almost at the junction of the Rio de la Plata and the Rio Uruguay. Renowned for offering spectacular sunsets from the promenade and pier. It has a spa, "Brisas del Uruguay", and within walking distance is Punta Gorda is the km 0 of the Río de la Plata.

- Located at the junction of Routes 12 and 21 (located 100 km from Colonia del Sacramento by the latter route)